Irf2bp2 cancer
WebIRF2BP2-NTRK1 Fusion is present in 0.02% of AACR GENIE cases, with sarcoma, NOS, breast invasive ductal carcinoma, gastric adenocarcinoma, lung adenocarcinoma, and pancreatic acinar cell carcinoma having the greatest prevalence [ 4 ]. Top Disease Cases with IRF2BP2-NTRK1 Fusion References 1. WebMar 19, 2024 · All-trans-retinoic acid (ATRA), 45 mg/m 2 in divided doses daily until clinical remission, plus arsenic trioxide (ATO), 0.15 mg/kg IV daily until bone marrow remission; alternatively, ATO may be given in a dose of 0.3 mg/kg IV on days 1–5 of week 1 and 0.25 mg/kg twice weekly during weeks 2–8. In the ATRA-ATO regimen, an ATRA dose of 25 mg ...
Irf2bp2 cancer
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WebMay 19, 2016 · The IRF2BP2–CDX-1 fusion gene has been reported in mesenchymal chondrosarcoma, 16 and there is one previous report of IRF2BP2–RARA in APL. 10 Yin et al. 10 reported a case of APL with IRF2BP2–RARA that involved exon 2 of IRF2BP2 and intron 2 of RARA, with breakpoints at positions 1687 bp in IRF2BP2 and 41620 bp in RARA. The … WebNational Center for Biotechnology Information
WebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of … WebIRF2BP2 INFORMATION. Proteini. Full gene name according to HGNC. Interferon regulatory factor 2 binding protein 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. IRF2BP2 (IRF-2BP2) Protein classi. Assigned HPA protein class (es) for the encoded protein (s).
WebObjective: Primary central nervous system lymphoma (PCNSL) is a specific type of non-Hodgkin lymphoma with poor prognosis. The rare incidence of this disease and difficulty to obtain sufficient tissue material impede deep research into PCNSL. However, application of modern molecular techniques makes it possible to find biological characteristics … WebIRF2BP2 is involved in 1 fusion, with the following gene: CDX1 (1 mutation in 4 samples) Drug sensitivity data Mutations in IRF2BP2 are associated with altered sensitivity to the following 10 drugs: Dactolisib Docetaxel SN-38 Show all See all drug sensitivity data for IRF2BP2. External links
WebJan 22, 2024 · IRF2BP2 is a novel HNF4α co-repressor: Its role in gluconeogenic gene regulation via biochemically labile interaction. Kouketsu T, Monma R, Miyairi Y, …
WebNov 22, 2016 · IRF2BP2 is a downstream target of p53 and repressor of the cell cycle regulator NFAT1 (refs 7, 8). IRF2BP2 is fused to CDX1 as a result of the t (1;5) (q42;q32) in mesenchymal chondrosarcoma... fisher electronicsWebSep 20, 2024 · In this study, we uncovered the clinical significance of IRF2BP2 in suppressing hepatocellular carcinogenesis. We showed that IRF2BP2, a direct target repressed by the Yes-associated protein … fisher electronics customer serviceWebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA. canadian armed forces file indexWebJul 20, 2015 · IRF2BP2 is a cofactor modulating IRF2 and myocyte enhancer factor 2 (MEF2), transcription factors important for innate immunity and gene expression in macrophages. 8 – 12 Exposure of macrophages to bacterial lipopolysaccharide activates the M1 inflammatory phenotype, whereas exposure to interleukin (IL)-4 favors the M2 anti … fisher electronics repairWebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... To access cancer specific RNA and … fisher electronics norwalkWebSep 20, 2024 · IRF2BP2 stabilized VGLL4 protein and repressed tumor progression via the inactivation of YAP-TEAD4 complex in liver cancer (41). In contrast, IRF2BP2 repressed … fisher electronics norwalk ohioWebApr 29, 2024 · The IRF2BP2 protein is found in different organisms and has been described as ubiquitously expressed in normal and tumor cells and tissues, indicating a possible role for this transcriptional... canadian armed forces fighter jets